Q-SAP™ – Quillaja Sustainable Adjuvant Platform is a technology platform combining computational learning techniques and a proprietary multi-step purification process.
To date, quillaja-based adjuvant development and production (including QS-21 and Quil-A) has focused on a highly restrictive quillaja source and a narrow chemistry spectrum significantly limiting availability and functionality.
Q-VANT is the first company to use a computational-driven approach to systematically enhance quillaja sourcing options and to drive extremely effective outputs of high quality QS-21 and Quil-A homologous production.
The revolutionary result of these discoveries has allowed Q-VANT to change the narrative for QS-21 availability by dramatically increasing the supply by more than one thousand times (leading to billions of doses) all in a 100% sustainable way.
Q-SAP™ Technology
- Q-SAP™ proprietary technology enables Q-VANT to obtain adjuvant products from a wide range of quillaja-based plant materials which can increase production volumes by as much as 1,000 times.
- Q-SAP™ combines a computational learning system in series with a proprietary multi-step purifying/ fractionating technology optimizing the production and purity of the QS-21 fraction (QS-21 INFINITY™).
- Our Q-SAP™ technology goes one step further to include in our research pipeline the development of new QS-21 versions with improved safety profiles, resulting in greater flexibility of use at higher doses and with less undesired effects.
Products |
Standard QS-21 |
QS-21 INFINITY™ |
| Adjuvant Properties | Excellent | Excellent |
| Raw Material | Quillaja bark wild harvested | Wide range of quillaja plant material |
| Sustainability | Only bark of old quillaja trees | Fully Sustainable- Increased volume by 1,000 times |
| Yield | Low | High |
| Purity | Standard | Standard |
| Stability | Standard | Standard |
| Doses per year | 20 million | 20 billion (X 1,000) |
| Cost | Expensive | Reduced cost |
| Regulation | Accepted | Accepted |
Products |
Standard QS-21 |
| Adjuvant Properties | Excellent |
| Raw Material | Quillaja bark wild harvested |
| Sustainability | Only bark of old quillaja trees |
| Yield | Low |
| Purity | Standard |
| Stability | Standard |
| Doses per year | 20 million |
| Tolerability | Limiting |
| Cost | Expensive |
| Regulation | Accepted |
Products |
QS-21 INFINITY® |
| Adjuvant Properties | Excellent |
| Raw Material | Wide range of quillaja plant material |
| Sustainability | Fully Sustainable- Increased volume by 1,000 times |
| Yield | High |
| Purity | Standard |
| Stability | Standard |
| Doses per year | 20 billion (X 1,000) |
| Tolerability | Limiting |
| Cost | Reduced cost |
| Regulation | Accepted |