Q-SAP™ proprietary technology enables Q-VANT to obtain adjuvant products from a wide range of quillaja-based plant materials, which can increase production volumes by as much as 1,000 times. Q-VANT is a pioneer in enhancing quillaja sourcing options and driving extremely effective outputs of high-quality QS-21 and other saponin adjuvants.
Q-SAP™ technology goes one step further to include in our research pipeline the development of novel QS-21 versions and saponin molecules with improved safety profiles, resulting in greater flexibility of use at higher doses and with less undesired effects.
Q-SAP™ combines a computational learning system in series with a proprietary multi-step purifying/fractionating technology optimizing the yield and purity of the QS-21 fraction (QS-21 INFINITY™).
Conventional supply: the bark story
To date, quillaja-based adjuvant development and production (including QS-21, ISCOM Matrix, Quil-A) has focused on a highly restrictive quillaja bark source and a narrow chemistry spectrum significantly limiting availability and functionality.
PRODUCTS |
TRADITIONAL PROCESS |
Q-SAP |
|---|---|---|
Raw Material |
Bark harvested from wild and mature Quillaja trees, availability is decreasing. |
Wide range of quillaja plant material |
Purity |
Standard |
Standard |
Stability |
Standard |
Standard |
Volume capability (doses) |
20 million and decreasing |
20 billion (X 1,000) |
Cost |
High and volatile |
Reduced and controlled |
Regulation gap |
None |
None |
More details |
