Q-SAP™ proprietary technology enables Q-VANT to obtain adjuvant products from a wide range of quillaja-based plant materials, which can increase production volumes by as much as 1,000 times. Q-VANT is a pioneer in enhancing quillaja sourcing options and driving extremely effective outputs of high-quality QS-21 and other saponin adjuvants.
Q-SAP™ technology goes one step further to include in our research pipeline the development of novel QS-21 versions and saponin molecules with improved safety profiles, resulting in greater flexibility of use at higher doses and with less undesired effects.
Q-SAP™ combines a computational learning system in series with a proprietary multi-step purifying/fractionating technology optimizing the yield and purity of the QS-21 fraction (QS-21 INFINITY™).
Conventional supply: the bark story
To date, quillaja-based adjuvant development and production (including QS-21, ISCOM Matrix, Quil-A) has focused on a highly restrictive quillaja bark source and a narrow chemistry spectrum significantly limiting availability and functionality.
PRODUCTS | TRADITIONAL PROCESS | Q-SAP |
|---|---|---|
Raw Material | Bark harvested from wild and mature Quillaja trees, availability is decreasing. | Wide range of quillaja plant material |
Purity | Standard | Standard |
Stability | Standard | Standard |
Volume capability (doses) | 20 million and decreasing | 20 billion (X 1,000) |
Cost | High and volatile | Reduced and controlled |
Regulation gap | None | None |
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